DEXTROCHLORPHENIRAMINE TANNATE

The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150.degree.C with tannic acid preferably neat or as an aqueous slurry containing about...

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Bibliographische Detailangaben
Hauptverfasser:	CHOPDEKAR, VILAS M, REDKAR, SHAM N, MELLOZZI, ANGELO R, ACHARI, RAJA G
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention pertains to a novel composition comprising dextrochlorpheniramine tannate and to a method for preparing such tannate by reacting dextrochlorpheniramine free base at a temperature of about 60 to about 150.degree.C with tannic acid preferably neat or as an aqueous slurry containing about 5 to about 30 wt.% water. The dextrochlorpheniramine tannate has extended release properties and is useful in pharmaceutical compositions as an antihistamine for human beings.