RENAL CELL CARCINOMA-ANTIGEN G250-DERIVED PEPTIDES THAT ELICIT BOTH CD4+ AND CD8+ T-CELL

The present invention relates to immunogenic peptides that can be used to elicit an immune response in a human or animal against a tumor, in particular again st an immunogenic tumor. The peptides are derived from the G250 tumor antigen that is frequently expressed on immunogenic tumors, such as rena...

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Bibliographische Detailangaben
Hauptverfasser:	DE VRIES, INGRID JOLANDA MONIQUE, VISSERS, JOOST LAMBERT MAX, FIGDOR, CARL GUSTAV, ADEMA, GOSSE JAN, OOSTERWIJK, EGBERT
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to immunogenic peptides that can be used to elicit an immune response in a human or animal against a tumor, in particular again st an immunogenic tumor. The peptides are derived from the G250 tumor antigen that is frequently expressed on immunogenic tumors, such as renal cell carcinoma. Th e particular peptides are selected for their capability to elicit both CD4+ an d CD8+ T-cell responses against cells expressing the G250 antigen.