MANUFACTURE AND PURIFICATION OF CYCLOSPORIN A

MANUFACTURE AND PURIFICATION OF CYCLOSPORIN A

The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and...

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Hauptverfasser: ANAND, KONAYAKANAHALLI NANJUNDA SWAMY, GANESH, SAMBASIVAM, SURYANARAYAN, SHRIKUMAR, SUBRAMANIYAM, PAMPAPATHY, SIRCAR, ANINDYA, TAMBE, SHREEHAS, PRADEEP, KHEDKAR, ANAND, PRAKASH, RAMKRISHNA, MELARKODE
Format: Patent
Sprache:eng ; fre
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BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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creator ANAND, KONAYAKANAHALLI NANJUNDA SWAMY
GANESH, SAMBASIVAM
SURYANARAYAN, SHRIKUMAR
SUBRAMANIYAM, PAMPAPATHY
SIRCAR, ANINDYA
TAMBE, SHREEHAS, PRADEEP
KHEDKAR, ANAND, PRAKASH
RAMKRISHNA, MELARKODE
description The present invention provides an improved method for the manufacture of Cyclosporin A is disclosed. Cyclosporin A is produced by solid state fermentation of Fusarium solani in a bioreactor under optimal fermentation parameters. The product is extracted and further purified by treating with alum and subsequent chromatographic procedures to get pharmaceutical acceptable purity.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
title MANUFACTURE AND PURIFICATION OF CYCLOSPORIN A
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