2,4,DI(HETERO-)ARYLAMINO(-OXY)-5-SUBSTITUTED PYRIMIDINES AS ANTINEOPLASTIC AGENTS
Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture , pharmaceutical compositions and their use as cyclin-dependent serine/threoni ne kinase...
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Zusammenfassung: | Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture , pharmaceutical compositions and their use as cyclin-dependent serine/threoni ne kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.< /SDOAB> |
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