SIGNAL SEQUENCES FOR PREPARING LEU-HIRUDIN BY SECRETION BY E. COLI INTO THE CULTURE MEDIUM

The present invention relates to a hirudin precursor comprising a signal sequence and the sequence of Leu-hirudin, to its preparation and use, and to a process for finding signal sequences for secretory expression of any desired proteins in E. coli and process for the secretory expression of any des...

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Bibliographische Detailangaben
Hauptverfasser:	HABERMANN, PAUL, BENDER, RUDOLF
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a hirudin precursor comprising a signal sequence and the sequence of Leu-hirudin, to its preparation and use, and to a process for finding signal sequences for secretory expression of any desired proteins in E. coli and process for the secretory expression of any desired proteins in E. coli.