USE OF PROTEINASE INHIBITOR IN ORDER TO INHIBIT THE CLEAVAGE OF GROWTH FACTOR PRECURSOR

The present description relates to agents, methods for growth-factor receptor activation by modulating the G-protein mediated signal transduction pathway. It is provided the use of a modulator which acts on a growth-factor precursor to inhibit the activation of the extracellular domain of a growth-f...

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Bibliographische Detailangaben
Hauptverfasser:	PRENZEL, NORBERT, ULLRICH, AXEL, ZWICK-WALLASCH, ESTHER, DAUB, HENRIK
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present description relates to agents, methods for growth-factor receptor activation by modulating the G-protein mediated signal transduction pathway. It is provided the use of a modulator which acts on a growth-factor precursor to inhibit the activation of the extracellular domain of a growth-factor receptor for the manufacture of a medicament for the prevention or treatment of cancers which are induced by G-protein mediated signal transduction wherein the medicament comprises the modulator in an amount sufficient to inhibit growth-factor receptor activation, wherein the modulator acts on proHB-EGF.