PROCESS FOR THE PREPARATION OF ACETAMIDE DERIVATIVES

PROCESS FOR THE PREPARATION OF ACETAMIDE DERIVATIVES

PROCESS FOR THE PREPARATION OF ACETAMIDE DERIVATIVES The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH2CONH2,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KASPI, JOSEPH, LERMAN, ORI, NADDAKA, VLADIMIR, SAEED, SHADI, MENASHE, NAIM, LEXNER, JAEL
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:PROCESS FOR THE PREPARATION OF ACETAMIDE DERIVATIVES The invention provides a process for the preparation of diphenylmethylthioacetamide (I) as described in Scheme 4 comprising reacting of the isothiouronium salt or its corresponding base of the formula IV with an acetamide of the formula XCH2CONH2, wherein X represents a halogen, M represents an alkali metal and A represents an anion, in a protic medium at a temperature of less than 100.degree. C.