ANTIPSYCHOTIC CYCLIC N-ARALKYLAMINES

ANTIPSYCHOTIC CYCLIC N-ARALKYLAMINES

The invention concerns antipsychotic compounds of formula (I) wherein: A represents a group selected among the following: -CaC-; -CH=CH-; -CH2-CH2-; n is equal to 1 or 2; X represents a hydrogen, chlorine or fluorine atom, a methyl or methoxy group; Y represents a hydrogen atom or a chlorine or a fl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LAIR, PIERRE, VERNIERES, JEAN-CLAUDE, PONCELET, MARTINE, BOIGEGRAIN, ROBERT, PAUL, RAYMOND, BOURRIE, MARTINE
Format: Patent
Sprache:eng ; fre
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention concerns antipsychotic compounds of formula (I) wherein: A represents a group selected among the following: -CaC-; -CH=CH-; -CH2-CH2-; n is equal to 1 or 2; X represents a hydrogen, chlorine or fluorine atom, a methyl or methoxy group; Y represents a hydrogen atom or a chlorine or a fluorine atom; R1 represents a cyclohexyl, phenyl, cycloheptyl, tertiary butyl, dicyclopropylmethyl, bicyclo[3.2.1]octanyl, 4-tetrahydropyranyl, 4- tetrahydrothiopyranyl or adamantyle group; R2 and R3 form together with the nitrogen atom whereto the y re bound a cyclic amine; and the additive salts of said compounds with pharmaceutically acceptable acids, as well as their solvates and hydrates.