PHARMACOLOGICAL SCREENING OF NEURONALLY ACTIVE SUBSTANCES

Pharmacological screening of neuronally active substances is effected by producing second lesion by non-lesion experimental animals by injection in the medial septum of the animal of an amount of vincristine effected by the purpose and administering the substances to be tested by the lesioned animal...

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Bibliographische Detailangaben
Hauptverfasser:	FOURNIER, JACQUELINE, GUZZI, UMBERTO, COUDE, FRANCOIS X
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES DIAGNOSIS ENZYMOLOGY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE IDENTIFICATION INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS SURGERY TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Pharmacological screening of neuronally active substances is effected by producing second lesion by non-lesion experimental animals by injection in the medial septum of the animal of an amount of vincristine effected by the purpose and administering the substances to be tested by the lesioned animals according to a suitably selected schedule. The effects of the treatment axe assessed by evaluation morphological changes, biochemical observation or behavioural observation.