TARGET MOLECULE ATTACHMENT TO SURFACES

Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in at...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GUIRE, PATRICK E, SWAN, DALE G, CHAPPA, RALPH A, SWANSON, MELVIN J, HU, SHEAU-PING
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:Method and reagent composition for covalent attachment of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of covalently binding to the target molecule. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface. The reagent composition can be used to provide activated slides for use in preparing microarrays of nucleic acids.