PROCESS FOR THE PREPARATION OF THE MESYLATE SALT TRIHYDRATE OF 1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDIN-1-YL)-1-PROPANOL AND INTERMEDIATES USEFUL THEREFOR

The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol: (see formula I) The present invention is further directed to a process for the preparation...

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Hauptverfasser:	WALINSKY, STANLEY WALTER, SINAY, TERRY GENE JR, RAINVILLE, JOSEPH PHILIP
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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creator	WALINSKY, STANLEY WALTER SINAY, TERRY GENE JR RAINVILLE, JOSEPH PHILIP
description	The present invention is directed to a novel process for the preparation of the mesylate trihydrate of the compound of formula (I), (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1-propanol: (see formula I) The present invention is further directed to a process for the preparation o f a (2S)-(+)- compound of formula (II): (see formula II) wherein R1 is a protecting group. In addition, the present invention relates to intermediates useful in said processes.
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In addition, the present invention relates to intermediates useful in said processes.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
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subjects	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
title	PROCESS FOR THE PREPARATION OF THE MESYLATE SALT TRIHYDRATE OF 1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDIN-1-YL)-1-PROPANOL AND INTERMEDIATES USEFUL THEREFOR
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