MUCOADHESIVE COMPOSITIONS FOR ADMINISTRATION OF BIOLOGICALLY ACTIVE AGENTS TO ANIMAL TISSUE

MUCOADHESIVE COMPOSITIONS FOR ADMINISTRATION OF BIOLOGICALLY ACTIVE AGENTS TO ANIMAL TISSUE

This invention pertains to mucoadhesive compositions for the delivery of pharmacologically active agents, and to polymeric formulations that allow for a prolonged, sustained release of the active agents. More specially the invention pertains to compositions for the delivery of drugs to mucosal tissu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: SHAH, KISHORE R
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention pertains to mucoadhesive compositions for the delivery of pharmacologically active agents, and to polymeric formulations that allow for a prolonged, sustained release of the active agents. More specially the invention pertains to compositions for the delivery of drugs to mucosal tissue, said composition comprising a drug or a plurality of drugs to be delivered and a thermoplastic graft copolymer, said graft copolymer being the reaction product of a polystyrene macromonomer having an ethylenically unsaturated functional group, and at least one acidic hydrophilic monomer having an ethylenically unsaturated functional group.