N-(3-ETHYNYLPHENYL-6,7-BIS(2-METHOXYETHOXY)-4-QUINAZOLINAMINE MESYLATE ANHYDRATE AND MONOHYDRATE

The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods o...

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Hauptverfasser: ALLEN, DOUGLAS JOHN MELDRUM, SANTAFIANOS, DINOS PAUL, RAGGON, JEFFREY WILLIAM, NORRIS, TIMOTHY, SHANKER, RAVI MYSORE
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creator ALLEN, DOUGLAS JOHN MELDRUM
SANTAFIANOS, DINOS PAUL
RAGGON, JEFFREY WILLIAM
NORRIS, TIMOTHY
SHANKER, RAVI MYSORE
description The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods of treating hyperproliferative disorders, such as cancer, by administering N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- quinazolinamine mesylate.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title N-(3-ETHYNYLPHENYL-6,7-BIS(2-METHOXYETHOXY)-4-QUINAZOLINAMINE MESYLATE ANHYDRATE AND MONOHYDRATE
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