N-(3-ETHYNYLPHENYL-6,7-BIS(2-METHOXYETHOXY)-4-QUINAZOLINAMINE MESYLATE ANHYDRATE AND MONOHYDRATE

The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods o...

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Hauptverfasser: ALLEN, DOUGLAS JOHN MELDRUM, SANTAFIANOS, DINOS PAUL, RAGGON, JEFFREY WILLIAM, NORRIS, TIMOTHY, SHANKER, RAVI MYSORE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to the anhydrous and hydrate forms of N-(3- ethynylphenyl)-6,7-bis (2-methoxyethoxy)4-quinazolinamine mesylate. The invention also relates to pharmaceutical compositions containing N- (3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate and to methods of treating hyperproliferative disorders, such as cancer, by administering N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- quinazolinamine mesylate.