USE OF APO B SECRETION/MTP INHIBITORS

The invention relates to methods and pharmaceutical compositions useful in reducing food intake in an animal, preferably a mammal including a human subject or a companion animal, using a microsomal triglyceride transfer protein apolipoprotein B (apo B) secretion/microsomal triglyceride transfer protein (MTP) inhibitor. The invention preferably relates to methods and pharmaceutical compositions usef ul in reducing food intake in an animal, preferably a mammal including a human subject or a companion animal, using an apo B secretion/MTP inhibitor, and an anti- obesity agent. The invention further relates to a kit comprising an amount of anapolipoprotein B secretion/microsomal triglyceride transfer protein inhibitor and a pharmaceutically acceptable carrier, vehicle or diluent in a first unit dosage form; an amoun t of an antiobesity agent and a pharmaceutically acceptable carrier, vehicle or diluent in a second unit dosage form; and a container.