BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME
The present invention relates to a barbituric acid derivative shown in formu la (I) (wherein R or R1 independently represents a hydrogen atom, a susbstitute d or not substituted alkyl group or alkenyl group of C1 - C15, a substituted o r not substituted arylmethyl group, and substituted or not subst...
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| creator | SATOH, YUSUKE SAKAI, KUNIKAZU |
| description | The present invention relates to a barbituric acid derivative shown in formu la (I) (wherein R or R1 independently represents a hydrogen atom, a susbstitute d or not substituted alkyl group or alkenyl group of C1 - C15, a substituted o r not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alken yl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative o f the present invention has a strong inhibiting activity to bone resorption an d is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.
The present invention relates to a barbituric acid derivative shown in formula (I) (wherein R or R1 independently represents a hydrogen atom, a susbstituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative of the present invention has a strong inhibiting activity to bone resorption and is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage. |
| format | Patent |
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The present invention relates to a barbituric acid derivative shown in formula (I) (wherein R or R1 independently represents a hydrogen atom, a susbstituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative of the present invention has a strong inhibiting activity to bone resorption and is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.</description><edition>6</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1999</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991007&DB=EPODOC&CC=CA&NR=2324584A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25555,76308</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19991007&DB=EPODOC&CC=CA&NR=2324584A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SATOH, YUSUKE</creatorcontrib><creatorcontrib>SAKAI, KUNIKAZU</creatorcontrib><title>BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME</title><description>The present invention relates to a barbituric acid derivative shown in formu la (I) (wherein R or R1 independently represents a hydrogen atom, a susbstitute d or not substituted alkyl group or alkenyl group of C1 - C15, a substituted o r not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alken yl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative o f the present invention has a strong inhibiting activity to bone resorption an d is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.
The present invention relates to a barbituric acid derivative shown in formula (I) (wherein R or R1 independently represents a hydrogen atom, a susbstituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative of the present invention has a strong inhibiting activity to bone resorption and is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1999</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNizEKwkAQRdNYiHqHuYCFSQTb2d1JMqCbME62DUHWQkQD8f6YoFhbfR7v_WVyMyiGtRW2gJYdOBIOqBwI0DtohAL5H2pFgg21OuflJKCoBUztP9qiKB8nAbb2iuzZl_MHzniidbK49vcxbr67SqAgtdU2Ds8ujkN_iY_46iymWZrvDznusj-SN-oxNTA</recordid><startdate>19991007</startdate><enddate>19991007</enddate><creator>SATOH, YUSUKE</creator><creator>SAKAI, KUNIKAZU</creator><scope>EVB</scope></search><sort><creationdate>19991007</creationdate><title>BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME</title><author>SATOH, YUSUKE ; SAKAI, KUNIKAZU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2324584A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1999</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>SATOH, YUSUKE</creatorcontrib><creatorcontrib>SAKAI, KUNIKAZU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SATOH, YUSUKE</au><au>SAKAI, KUNIKAZU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME</title><date>1999-10-07</date><risdate>1999</risdate><abstract>The present invention relates to a barbituric acid derivative shown in formu la (I) (wherein R or R1 independently represents a hydrogen atom, a susbstitute d or not substituted alkyl group or alkenyl group of C1 - C15, a substituted o r not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alken yl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative o f the present invention has a strong inhibiting activity to bone resorption an d is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.
The present invention relates to a barbituric acid derivative shown in formula (I) (wherein R or R1 independently represents a hydrogen atom, a susbstituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group, and R2 represents substituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative of the present invention has a strong inhibiting activity to bone resorption and is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME |
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