A DRIED OR FROZEN PHARMACEUTICAL PREPARATION CONTAINING A CLASS III ANTIARRHYTHMIC COMPOUND

The present invention relates to dried preparations containing a class III antiarriythmic compound in the form of crystalline or amorphous salt or any combination thereof, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. The present inventio...

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Bibliographische Detailangaben
Hauptverfasser: GRANATH, ANNA-KARIN, BJORE, ANNIKA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to dried preparations containing a class III antiarriythmic compound in the form of crystalline or amorphous salt or any combination thereof, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. The present invention also relates to frozen preparations containing a class III antiarrhythmic coumpound in the form of salt solution, where the counterion is selected from pharmaceutically acceptable water-soluble organic or inorganic acids. Preferred preparations contain a salt of the compound 3,7-diazabicyclo¢3.3.1!-nonane-3-carboxylic acid, 7-¢(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl!-1,1-dimethylethyl ester (Compound A). Further aspects of the present invention include salts of Compound A per se, processes for preparing the preparation, as well as use of the preparations for prophylaxis and/or treatment of cardiac arrhythmia.