NOVEL SALTS OF METFORMIN AND METHOD

Novel salts of the antidiabetic agent metformin are provided which are metformin salts of dibasic acids (2:1 molar ratio), preferably metformin (2:1) fumarate and metformin (2:1) succinate, which may be employe d alone or in combination with another antihyperglycemic agent such as glyburide, for tre...

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Hauptverfasser: POWERS, GERALD L, BRETNALL, ALISON, WEI, CHENKOU, SRIVASTAVA, SUSHIL K, WINTER, WILLIAM J, TIMMINS, PETER
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creator POWERS, GERALD L
BRETNALL, ALISON
WEI, CHENKOU
SRIVASTAVA, SUSHIL K
WINTER, WILLIAM J
TIMMINS, PETER
description Novel salts of the antidiabetic agent metformin are provided which are metformin salts of dibasic acids (2:1 molar ratio), preferably metformin (2:1) fumarate and metformin (2:1) succinate, which may be employe d alone or in combination with another antihyperglycemic agent such as glyburide, for treating diabetes. A method for treating diabet es employing the novel metformin salt by itself or in combination with another antidiabetic agent is also provided.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL SALTS OF METFORMIN AND METHOD
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