NOVEL SALTS OF METFORMIN AND METHOD

NOVEL SALTS OF METFORMIN AND METHOD

Novel salts of the antidiabetic agent metformin are provided which are metformin salts of dibasic acids (2:1 molar ratio), preferably metformin (2:1) fumarate and metformin (2:1) succinate, which may be employe d alone or in combination with another antihyperglycemic agent such as glyburide, for tre...

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Bibliographische Detailangaben
Hauptverfasser: POWERS, GERALD L, BRETNALL, ALISON, WEI, CHENKOU, SRIVASTAVA, SUSHIL K, WINTER, WILLIAM J, TIMMINS, PETER
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Novel salts of the antidiabetic agent metformin are provided which are metformin salts of dibasic acids (2:1 molar ratio), preferably metformin (2:1) fumarate and metformin (2:1) succinate, which may be employe d alone or in combination with another antihyperglycemic agent such as glyburide, for treating diabetes. A method for treating diabet es employing the novel metformin salt by itself or in combination with another antidiabetic agent is also provided.