NOVEL PROCESS FOR SYNTHESIZING PARA-AND/OR META-SUBSTITUTED CYANOPHENYLALANINE DERIVATIVES

The present invention relates to a process for preparing a useful medicinal intermediate represented by the following formula (1): (see formula I) in which, R1, A and n are defined as described in the specification, or its stereoisomer, characterized in that a compound represented by the following f...

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Bibliographische Detailangaben
Hauptverfasser: NAM, DO HYUN, KIM, BONG CHAN, LIM, JONG CHAN, SHIN, HYUN IK, HWANG, SANG YEUL
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to a process for preparing a useful medicinal intermediate represented by the following formula (1): (see formula I) in which, R1, A and n are defined as described in the specification, or its stereoisomer, characterized in that a compound represented by the following formula (2): (see formula II) in which, R, R1, A and n are defined as described in the specification, is reacted with a cyanide in the presence of a nickel catalyst.