HOLLOW FIBER CO-FLOW FILTRATION DEVICE

The present invention is directed to hollow fiber membrane filtration module s and processes useful for improved tangential flow filtration-mediated purification and separation of molecules from mixtures o f molecules, wherein those molecules may be of biological interest. The hollow fiber membrane...

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Bibliographische Detailangaben
1. Verfasser:	VAN REIS, ROBERT D
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SEPARATION SPIRITS TRANSPORTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention is directed to hollow fiber membrane filtration module s and processes useful for improved tangential flow filtration-mediated purification and separation of molecules from mixtures o f molecules, wherein those molecules may be of biological interest. The hollow fiber membrane filtration modules of the present invention are such that the transmembrane pressure along the entire length of the hollow fibers is substantially constant, thereby providing enhanced filtration capabilities, especially for large-scale recombinant protein purification. The hollow fiber filtration modules of the present invention may be employed either with or without co-current recirculation of the filtrate.