PROCESS FOR THE PRODUCTION OF HEPARIN

PROCESS FOR THE PRODUCTION OF HEPARIN

The invention relates to a simplified process for the extraction of heparin from animal mucosa tissue. The method consists of an enzymatic hydrolysis step of the raw material at ambient temperature, followed by hydrolysis for up to 6 hours at a temperature of 50-75 ~C. Raise in temperature is obtain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN ZUTPHEN, PETRUS JOHANNES JOSEPHUS, VAN HOUDENHOVEN, FRANCOIS EGBERT ABRAHAM, SANDERS, ADRIANUS LAMBERTUS MARIA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
POLYSACCHARIDES
THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:The invention relates to a simplified process for the extraction of heparin from animal mucosa tissue. The method consists of an enzymatic hydrolysis step of the raw material at ambient temperature, followed by hydrolysis for up to 6 hours at a temperature of 50-75 ~C. Raise in temperature is obtained by easy means. The digestion mixture can be further incubated while cooling down to ambient temperature. Heparin is recovered from anion exchanger present in the protein hydrolysate.