PROCESS FOR PRODUCING UCN-01

UCN-01 with anti-cancer activity and anti-bacterial activity is produced from UCN-02 in a simple and efficient manner. According to the process of the present invention, a solution containing UCN-02 is acidified to isomerize UCN-02 to UCN-01, whereby UCN-01 is recovered from the acidified solution.

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Bibliographische Detailangaben
Hauptverfasser:	NAGAMURA, SATORU, KINO, MITSUTAKA, AOKI, HIDENORI, TAKIGUCHI, TOSHIMITSU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	UCN-01 with anti-cancer activity and anti-bacterial activity is produced from UCN-02 in a simple and efficient manner. According to the process of the present invention, a solution containing UCN-02 is acidified to isomerize UCN-02 to UCN-01, whereby UCN-01 is recovered from the acidified solution.