HAPTEN-CARRIER CONJUGATES FOR USE IN DRUG-ABUSE THERAPY AND METHODS FOR PREPARATION OF SAME

Hapten-carrier conjugates capable of eliciting anti-hapten anti--bodies in vivo are described. Methods of preparing said conjugates and therapeutic compositions are also described. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier con-jugate is particularly...

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Hauptverfasser: SWAIN, PHILIP A, GEFTER, MALCOLM L, FOX, BARBARA S, EXLEY, MARK A, GREENSTEIN, JULIA L, POWERS, STEPHEN P
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Hapten-carrier conjugates capable of eliciting anti-hapten anti--bodies in vivo are described. Methods of preparing said conjugates and therapeutic compositions are also described. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier con-jugate is particularly useful in the treatment of a drug addiction. The therapeutic composition is suitable for co-therapy with other conven-tional drugs. Passive immunization using antibodies raised against th e hapten-carrier conjugates of the invention are also described.