METHOD FOR MEASURING VIRAL INFECTIVITY

The instant invention addresses the need for a more accurate method of quantitating infectious viral particles in a population. The methods of the instant invention are based on the unexpected and surprising result that flow cytometry analysis of cells infected at a low ratio of particle number to c...

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Bibliographische Detailangaben
Hauptverfasser: NUNNALLY, MARY H, SUGARMAN, BARRY J, HUTCHINS, BETH M
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The instant invention addresses the need for a more accurate method of quantitating infectious viral particles in a population. The methods of the instant invention are based on the unexpected and surprising result that flow cytometry analysis of cells infected at a low ratio of particle number to cell number yields a more accurate measurement of infectious virus titer than traditional titration methods.