PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES

A novel process makes it possible to produce optically active amines of the formula (I*) in which R and R1 have the meanings given in the description, by reacting a) in a first step, racemic amines of the formula (I) with esters of the formula (II), in which R3 and R4 have the meanings given in the...

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Bibliographische Detailangaben
1. Verfasser:	STELZER, UWE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS BASIC ELECTRIC ELEMENTS BEER BIOCHEMISTRY CHEMISTRY ELECTRICITY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE MEASURING MEASURING QUANTITY OF HEAT MEASURING TEMPERATURE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PHYSICS RESISTORS SPIRITS TESTING THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR VINEGAR WINE
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Beschreibung
Zusammenfassung:	A novel process makes it possible to produce optically active amines of the formula (I*) in which R and R1 have the meanings given in the description, by reacting a) in a first step, racemic amines of the formula (I) with esters of the formula (II), in which R3 and R4 have the meanings given in the description, in the presence of hydrolases and possibly a diluent, b) in a second step, the mixture obtained is separated into (S) amine of the formula (I-S) and acylated (R) amine of the formula (III) and c) optionally in a third step (R) amine of the formula (I-R) is released from acylated (R) amine of the formula (III) b y treatment with an acid or base, possibly in the presence of a diluent. Acylated (R) amines of the formula (IIIa) in which R11, R12, R13, X and p have the meanings given in the description.