SCREENING TEST FOR EARLY DETECTION OF COLORECTAL CANCER

A method for detecting neoplasia or cancer of the colon or rectum comprising obtaining a sample of colorectal mucus from the rectum of a patient, and detecting the presence of a marker selected from the group consisting of CH3(CH2)14CHO; CH3(CH2)16CHO; and plasmalogen-bound precursors thereof. Prefe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KREPINSKY, JIRI J, CHOCIEJ, JACEK
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	A method for detecting neoplasia or cancer of the colon or rectum comprising obtaining a sample of colorectal mucus from the rectum of a patient, and detecting the presence of a marker selected from the group consisting of CH3(CH2)14CHO; CH3(CH2)16CHO; and plasmalogen-bound precursors thereof. Preferably the method comprises treating the sample with Schiff's reagent and detecting neoplasia or cancer of the colon or rectum based upon the coloration produced at about 560 nm in the sample by the treatment. The method does not require the step of adding an enzyme for detecting the disaccharide marker .beta.-D-Gal(1-3)-D-GalNAc(.alpha.1-Thr/Ser).