A PROCESS FOR PURIFICATION OF K-252A

A PROCESS FOR PURIFICATION OF K-252A

The present invention provides a purification process of K-252a, which comprises: treating microorganism cells containing K-252a represented by formula (I) (See formula I) with an alkaline solution to convert K-252a into K-252b represented by formula (II) (See formula II) or alkali salts thereof, wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KINO, MITSUTAKA, NAGAMURA, SATORU, KINOSHITA, TADASHI
Format: Patent
Sprache:eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HETEROCYCLIC COMPOUNDS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present invention provides a purification process of K-252a, which comprises: treating microorganism cells containing K-252a represented by formula (I) (See formula I) with an alkaline solution to convert K-252a into K-252b represented by formula (II) (See formula II) or alkali salts thereof, which are then released out of the cells, methylating K-252b or alkali salts thereof to convert them into K-252a again, and isolating and collecting the resulting K-252a.