PROCESS FOR PROTEIN REFOLDING BY MEANS OF BUFFER EXCHANGE USING A CONTINUOUS STATIONARY PHASE CAPABLE OF SEPARATING PROTEINS FROM SALT

Disclosed is a quick and efficient refolding process which utilizes cellulos ic rolled stationary phase to rapidly separate the reduced, denatured protein from the denaturant solution, thereby promoting high protein refold yields a t higher protein concentrations, while significantly decreasing the volume needed to achieve protein refolding.