SIALIC ACID DERIVATIVES

SIALIC ACID DERIVATIVES

Sialic acid derivatives represented by general formula (1AA) and further derivatives thereof: wherein R1 represents a residue of cholestane or other steroidal compound; R2 represents hydrogen or methyl; R3 represents C1-C6 alkyl, etc.; R4 represents hydrogen or acyl; R5 represents R15O- (R15 being C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JIKIHARA, TETSUO, YUGAMI, TOMOKO, SAITO, KEN-ICHI, ANDO, NAOKO, CHAKI, HARUYUKI
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PHYSICS
STEROIDS
SUGARS
TESTING
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Beschreibung
Zusammenfassung:Sialic acid derivatives represented by general formula (1AA) and further derivatives thereof: wherein R1 represents a residue of cholestane or other steroidal compound; R2 represents hydrogen or methyl; R3 represents C1-C6 alkyl, etc.; R4 represents hydrogen or acyl; R5 represents R15O- (R15 being C2C7acyl) etc.; and X represents oxygen or sulfur. These derivatives have the effect of enhancing a choline acetyltransferase activity in cholinergic neurons and are useful for preventing and treating dementia, memory disorder, peripheral nerve disorder, and so forth.