CANINE FACTOR VIII GENE, PROTEIN AND METHODS OF USE

CANINE FACTOR VIII GENE, PROTEIN AND METHODS OF USE

The present invention provides isolated nucleic acid molecules encoding canine factor VIII and allelic variants, mutants, fragments or derivatives there of. The invention also provides canine factor VIII polypeptides encoded by such isolated nucleic acid molecules, antibodies binding to such polypep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NOTLEY, COLLEEN, HOUGH, CHRISTINE, CAMERON, CHERIE, HORROCKS, L. SUZANNE HOYLE, LILLICRAP, DAVID
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention provides isolated nucleic acid molecules encoding canine factor VIII and allelic variants, mutants, fragments or derivatives there of. The invention also provides canine factor VIII polypeptides encoded by such isolated nucleic acid molecules, antibodies binding to such polypeptides, geneti c constructs comprising such nucleic acid molecules, prokaryotic or eukaryotic hos t cells comprising such genetic constructs, and methods and compositions for use in diagnosing and treating canine disorders characterized by factor VIII deficiency.