ACELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF
A cellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 % of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particu...
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| creator | BARRETO, LUIS VOSE, JOHN R THIPPHAWONG, JOHN JACKSON, GAIL E.D BOUX, LESLIE FAHIM, RAAFAT E.F KLEIN, MICHEL H TAN, LARRY U.L HERBERT, ANDREW |
| description | A cellular pertussis vaccines comprise purified toxin or toxoid thereof, filamentous haemagglutinin, pertactin and fimbrial agglutinogens formulated to confer protection to at least 70 % of members of an at-risk population. The fimbrial agglutinogens may be prepared from a Bordetella strain, particularly a B. pertussis strain by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. |
| format | Patent |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | ACELLULAR PERTUSSIS VACCINES AND METHODS OF PREPARATION THEREOF |
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