NOVEL RECEPTOR

A receptor in substantially pure form obtainable from rat forebrain tissue which is characterised in that: a) compound A binds to it with a Kd of 40nM for rat forebrain tissue, b) compound A binds to it with a Bmax of 220 pmol/g protein for rat forebrain tissue, c) compound B binds to it with a Kd o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	JERMAN, JEFFREY CLIFFORD, HERDON, HUGH JONATHAN, CHAN, WAI NGOR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS THEREFOR BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	A receptor in substantially pure form obtainable from rat forebrain tissue which is characterised in that: a) compound A binds to it with a Kd of 40nM for rat forebrain tissue, b) compound A binds to it with a Bmax of 220 pmol/g protein for rat forebrain tissue, c) compound B binds to it with a Kd of 2nM for rat forebrain tissue, d) compound B binds to it with a Bmax of 220pmol/g protein for rat forebrain tissue; and homologous receptors from other sources sharing at least 85 % homology with the rat forebrain tissue.