INJECTION-MOLDED DOSAGE FORM

The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for ex...

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Hauptverfasser: FERRARI, VINCENT JOSEPH, POLLOCK, CRYSTAL, DONG, LIANG C, WONG, PATRICK S.-L
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creator FERRARI, VINCENT JOSEPH
POLLOCK, CRYSTAL
DONG, LIANG C
WONG, PATRICK S.-L
description The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for expanding for pushing the therapeutic composition from the dosage form in the compartment; (d) exit means in the dosage form that connects the therapeutic composition with the environment of use, and wherein the dosage form is characterized by: (e) an injection-molded membrane with a softening point below 200.degree.C, permeable to the passage of fluid that surrounds and defines the internal compartment, the injection-molded membrane comprising (i) polycaprolactone or a polycaprolactone copolymer; and (ii) one or more members selected from poly(alkylene oxide) and poly(ethylene glycol).
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language eng ; fre
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subjects CHEMISTRY
COMPOSITIONS BASED THEREON
COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SEPARATION
THEIR PREPARATION OR CHEMICAL WORKING-UP
TRANSPORTING
title INJECTION-MOLDED DOSAGE FORM
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