INJECTION-MOLDED DOSAGE FORM

The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for ex...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	FERRARI, VINCENT JOSEPH, POLLOCK, CRYSTAL, DONG, LIANG C, WONG, PATRICK S.-L
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SEPARATION THEIR PREPARATION OR CHEMICAL WORKING-UP TRANSPORTING
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Beschreibung
Zusammenfassung:	The present application discloses a dosage form for delivering a therapeutic agent to an environment of use, the dosage form comprising: (a) an internal compartment; (b) a therapeutic composition comprising a therapeutic agent in the compartment; (c) an expandable composition comprising means for expanding for pushing the therapeutic composition from the dosage form in the compartment; (d) exit means in the dosage form that connects the therapeutic composition with the environment of use, and wherein the dosage form is characterized by: (e) an injection-molded membrane with a softening point below 200.degree.C, permeable to the passage of fluid that surrounds and defines the internal compartment, the injection-molded membrane comprising (i) polycaprolactone or a polycaprolactone copolymer; and (ii) one or more members selected from poly(alkylene oxide) and poly(ethylene glycol).