FUSION PROTEINS COMPRISING GM-CSF AND ANTIGENS AND THEIR EXPRESSION IN YEAST

FUSION PROTEINS COMPRISING GM-CSF AND ANTIGENS AND THEIR EXPRESSION IN YEAST

Novel fusion proteins that enhance the immune response of an antigen are efficiently expressed and secreted by yeast host cells. The fusion proteins are recombinantly made by fusing the 3'-end of mature GM-CSF DNA to the 5'-e nd of an antigen DNA with or without a linker sequence. Methods...

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1. Verfasser: PRICE, VIRGINIA LEE
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Novel fusion proteins that enhance the immune response of an antigen are efficiently expressed and secreted by yeast host cells. The fusion proteins are recombinantly made by fusing the 3'-end of mature GM-CSF DNA to the 5'-e nd of an antigen DNA with or without a linker sequence. Methods of expression i n yeast cells are provided.