PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT

The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisphosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis. La...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: VAANANEN, KALERVO, LAUREN, LEENA, LIUKKO-SIPI, SIRPA, SELLMAN, RAIJA, KLEIMOLA, TERTTU, HEIKKILA-HOIKKA, MARJAANA, HANNUNIEMI, RITVA, NIKANDER, HANNU
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisphosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis. La présente invention concerne certains tétraalkyle esters de l'acide pyridinylaminométhylidène bisphosphonique, portant éventuellement des substitutions de cycle et ayant la formule (I), ainsi que leur utilisation dans le traitement de maladies des os telles que les maladies ostéolytiques dues à des tumeurs, la maladie osseuse de Paget et l'ostéoporose primaire ou secondaire.