PEPTIDES INHIBITING PHOSPHOLIPASE C

Peptides inhibiting phospholipase C which are represented by general formula (I), wherein n represents 0 or 1; J1 and J2 represent each hydrogen or form together a single bond; W represents hydrogen, optionally substituted alkanoyl, optionally substituted aroyl or coumaryl; X represents a single bon...

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Hauptverfasser: HONMA, YOSHIMI, YAMASAKI, MOTOO, ISHIKAWA, GENKICHI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Peptides inhibiting phospholipase C which are represented by general formula (I), wherein n represents 0 or 1; J1 and J2 represent each hydrogen or form together a single bond; W represents hydrogen, optionally substituted alkanoyl, optionally substituted aroyl or coumaryl; X represents a single bond, -Leu- or -Ser-Leu-Val-Glu-Leu-Val-Ser-Tyr-Tyr-Glu-Lys-His-Ala-Leu optionally having the deletion, insertion or replacement of at least one amino acid residue; Y represents a single bond or -Pro-Val-; R1 represents hydrogen, optionally substituted alkyl or optionally substituted aryl; and R2 represents optionally substituted alkyl or optionally substituted aryl.