HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS
Heteroaryl compounds of structure where X is -O-, -S-, -NH-, or -NR2- and Q1 is a substituted piperidine, pyrrolidine, or piperazine are useful as antipsychotic and analgesic agents. The compounds a re especially useful for treating psychoses by administering to a mammal a psychoses- treating effect...
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| creator | GLAMKOWSKI, EDWARD J HELSLEY, GROVER C STRUPCZEWSKI, JOSEPH T TEGELER, JOHN J BORDEAU, KENNETH J NEMOTO, PETER A CHIANG, YULIN |
| description | Heteroaryl compounds of structure where X is -O-, -S-, -NH-, or -NR2- and Q1 is a substituted piperidine, pyrrolidine, or piperazine are useful as antipsychotic and analgesic agents. The compounds a re especially useful for treating psychoses by administering to a mammal a psychoses- treating effective amount of one of the compounds. Depot derivatives of the compounds are usefu l for providing long acting effects of the compounds. The compounds are also usefu l as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal. |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS |
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