HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS

Heteroaryl compounds of structure where X is -O-, -S-, -NH-, or -NR2- and Q1 is a substituted piperidine, pyrrolidine, or piperazine are useful as antipsychotic and analgesic agents. The compounds a re especially useful for treating psychoses by administering to a mammal a psychoses- treating effect...

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Hauptverfasser: GLAMKOWSKI, EDWARD J, HELSLEY, GROVER C, STRUPCZEWSKI, JOSEPH T, TEGELER, JOHN J, BORDEAU, KENNETH J, NEMOTO, PETER A, CHIANG, YULIN
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Sprache:eng ; fre
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Zusammenfassung:Heteroaryl compounds of structure where X is -O-, -S-, -NH-, or -NR2- and Q1 is a substituted piperidine, pyrrolidine, or piperazine are useful as antipsychotic and analgesic agents. The compounds a re especially useful for treating psychoses by administering to a mammal a psychoses- treating effective amount of one of the compounds. Depot derivatives of the compounds are usefu l for providing long acting effects of the compounds. The compounds are also usefu l as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.