METHOD OF INCREASING VIABILITY OF STORED ERYTHROCYTES BY ADDITION OF LIPOIC, DIHYDROLIPOIC, 6,8-BISNORTETRALIPOIC OR TETRANORLIPOIC ACID

In comparison with currently used methods for storing blood, the following advantages could be achieved by the addition according to the invention of D,L-.alpha.-lipoic acid and/or the enantiomers thereof and/or the derivatives thereof before storage: the properties of erythrocyte concentrates at 4°...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CONRAD, FRANK, HENRICH, HERMANN-AUGUST, GEISE, WOLFGANG, ULRICH, HEINZ
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TRAPPING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	In comparison with currently used methods for storing blood, the following advantages could be achieved by the addition according to the invention of D,L-.alpha.-lipoic acid and/or the enantiomers thereof and/or the derivatives thereof before storage: the properties of erythrocyte concentrates at 4°C could be improved with regard to their oxygen release capacity (2,3-DPG) and viscoelasticity and with regard to membrane peroxidation during storage and for subsequent transfusion by means of the above-stated bodily, i.e. physiological substance. The same applies to cryogenically stored erythrocytes which are additionally protected from damage by the freeze/thaw process and the erythrocyte aggregability of which is improved.