NEW GLUCOCORTICOIDS

Glucocorticoids have the general formula (I): R-Val-O-GC, in which O-GC stands for the rest of an anti-inflammatory 21-hydroxycorticoid, Val stands for a valine residue located at the 21st position of the corticoid and R stands for a hydrogen atom or for a hydrocarbon residue having up to 32 carbon...

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Bibliographische Detailangaben
Hauptverfasser: ZENTEL, HANS JOACHIM, BRUMBY, THOMAS, ESPERLING, PETER, TOEPERT, MICHAEL, LAURENT, HENRY
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Glucocorticoids have the general formula (I): R-Val-O-GC, in which O-GC stands for the rest of an anti-inflammatory 21-hydroxycorticoid, Val stands for a valine residue located at the 21st position of the corticoid and R stands for a hydrogen atom or for a hydrocarbon residue having up to 32 carbon atoms and if required substituted by hydroxy groups, amino groups, oxo groups and/or halogen atoms and/or interrupted by oxygen atoms, SO2 groups and/or NH groups. Also disclosed are the salts of said corticoids.