POTENTIATION OF TEMOZOLOMIDE IN HUMAN TUMOUR CELLS

The toxicity of temozolomide an anti-tumour agent useful in the treatment of various mammalian neoptasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O6-benzylguanine.

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Bibliographische Detailangaben
Hauptverfasser:	WATSON, AMANDA JEAN, FREEMAN, AZADEH ALISON, MARGISON, GEOFFREY PAUL, NEWLANDS, EDWARD STUART, BAER, JOHN COLIN, RAFFERTY, JOSEPH ANTHONY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The toxicity of temozolomide an anti-tumour agent useful in the treatment of various mammalian neoptasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O6-benzylguanine.