Potentiation of Temozolomide in Human Tumour Cells

The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	WATSON, AMANDA JEAN, FREEMAN, AZADEH ALISON, MARGISON, GEOFFREY PAUL, NEWLANDS, EDWARD STUART, BAER, JOHN COLIN, RAFFERTY, JOSEPH ANTHONY
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O -benzylguanine.