PHOSPHOLIPASE C-INHIBITING PEPTIDES

The present invention relates to phopholipase C-inhibiting peptides which are represented by formula (I): wherein J1 and J2 are each hydrogen or combined together to form a single bond; W is hydrogen, a substituted or unsubstituted alkanoyl, a substituted or unsubstituted aroyl or coumaryl; X is a s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HONMA, YOSHIMI, YAMASAKI, MOTOO, ISHIKAWA, GENKICHI
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to phopholipase C-inhibiting peptides which are represented by formula (I): wherein J1 and J2 are each hydrogen or combined together to form a single bond; W is hydrogen, a substituted or unsubstituted alkanoyl, a substituted or unsubstituted aroyl or coumaryl; X is a single bond, -Leu- or -Ser-Leu-Val-Glu-Leu-Val-Ser-Tyr-Tyr-Glu-Lys-His-Ala-Leu- (at least one of the N-terminal 14 amino acid residues may be deleted); Y is a single bond or -Pro-Val-; and Z is hydroxy or amino.