USE OF 17.ALPHA.-DIHYDROEQUILENIN FOR LOWERING CHOLESTEROL

USE OF 17.ALPHA.-DIHYDROEQUILENIN FOR LOWERING CHOLESTEROL

2148357 9409789 PCTABS00032 This invention provides a method of lowering cholesterol and blood lipid levels, preventing hypercholesterolemia, hyperlipidemia, cardiovascular disease, atherosclerosis, and peripheral vascular disease comprising administering an effective amount of 17.alpha.-dihydroequi...

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Bibliographische Detailangaben
Hauptverfasser: DEY, MICHAEL STEVEN, WASCHBURN, SCOTT ALAN, CLARKSON, THOMAS BOSTON, ADELMAN, STEVEN JAY
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:2148357 9409789 PCTABS00032 This invention provides a method of lowering cholesterol and blood lipid levels, preventing hypercholesterolemia, hyperlipidemia, cardiovascular disease, atherosclerosis, and peripheral vascular disease comprising administering an effective amount of 17.alpha.-dihydroequilenin or a mammalian metabolic conjugate thereof, including a pharmaceutically acceptable salt thereof, to a mammal in need thereof. The invention also provides a compound for use as a pharmaceutical, the compound being selected from 17.alpha.-dihydroequilenin, a mammalian metabolic conjugate thereof and their pharmaceutically acceptable salts. The invention also provides a pharmaceutical composition comprising the said compound in association or combination with a pharmaceutical carrier.