A PROCESS FOR THE PREPARATION OF (-)-ESERETHOLE FROM MIXTURES OF (-) AND (+)-ESERETHOLE

A process for the preparation of (-)-eserethole, of formula (I) starting fro m (~)-eserethole, or from mixtures of (+)-and (-)-eserethole in which the latter enantiomer prevails by treating (~)- eserethole or mixtures of (~)- and (-)-eserethole enriched in the latter enantiomer, with 0.5-0.7 mole (p...

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Hauptverfasser: MAIORANA, STEFANO, BELLI, ALDO, CHIODINI, GIORGIO
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creator MAIORANA, STEFANO
BELLI, ALDO
CHIODINI, GIORGIO
description A process for the preparation of (-)-eserethole, of formula (I) starting fro m (~)-eserethole, or from mixtures of (+)-and (-)-eserethole in which the latter enantiomer prevails by treating (~)- eserethole or mixtures of (~)- and (-)-eserethole enriched in the latter enantiomer, with 0.5-0.7 mole (per mole of the enantiomeric mixture) of a resolution agent, to yield a (-)-eserethole salt less soluble than the corresponding (+)-eserethole salt.
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subjects APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title A PROCESS FOR THE PREPARATION OF (-)-ESERETHOLE FROM MIXTURES OF (-) AND (+)-ESERETHOLE
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