A PROCESS FOR THE PREPARATION OF (-)-ESERETHOLE FROM MIXTURES OF (-) AND (+)-ESERETHOLE

A PROCESS FOR THE PREPARATION OF (-)-ESERETHOLE FROM MIXTURES OF (-) AND (+)-ESERETHOLE

A process for the preparation of (-)-eserethole, of formula (I) starting fro m (~)-eserethole, or from mixtures of (+)-and (-)-eserethole in which the latter enantiomer prevails by treating (~)- eserethole or mixtures of (~)- and (-)-eserethole enriched in the latter enantiomer, with 0.5-0.7 mole (p...

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Bibliographische Detailangaben
Hauptverfasser: MAIORANA, STEFANO, BELLI, ALDO, CHIODINI, GIORGIO
Format: Patent
Sprache:eng ; fre
Schlagworte:
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A process for the preparation of (-)-eserethole, of formula (I) starting fro m (~)-eserethole, or from mixtures of (+)-and (-)-eserethole in which the latter enantiomer prevails by treating (~)- eserethole or mixtures of (~)- and (-)-eserethole enriched in the latter enantiomer, with 0.5-0.7 mole (per mole of the enantiomeric mixture) of a resolution agent, to yield a (-)-eserethole salt less soluble than the corresponding (+)-eserethole salt.