IMMUNOASSAY AND TEST KIT FOR THROMBIN-ANTITHROMBIN III COMPLEX

The present invention provides an immunoassay for thrombin-antithrombin complex in a human fluid sample. The assay comprises reaction of a human fluid sample with at least two antibodies or immunoreactive fragments thereof, wherein at least one of the antibodies binds to thrombin-antithrombin III co...

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Bibliographische Detailangaben
Hauptverfasser: ARBUTHNOTT, KATHRYN, RUIZ, JUAN A, MCINERNEY, MARGARET, MILLER, STEVE, MUSTAIN, ERIC L, PEREZ-TEJIDOR, LILIANA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides an immunoassay for thrombin-antithrombin complex in a human fluid sample. The assay comprises reaction of a human fluid sample with at least two antibodies or immunoreactive fragments thereof, wherein at least one of the antibodies binds to thrombin-antithrombin III complex in the sample, but exhibits essentially no cross-reactivity with antithrombin III and complexes of antithrombin III with other serine proteaste factors.