ASYMMETRIC SYNTHESIS OF (S) - (+) -N,N-DIMETHYL-3-(1-NAPHTHALENYLOXY)-3-(2-THIENYL)PROPANAMINE

This invention provides a stereospecific process for the synthesis of (S)-(+)-N,N-dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine, a key intermediate in the synthesis of duloxetine.

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Bibliographische Detailangaben
1. Verfasser:	BERGLUND, RICHARD A
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM APPARATUS THEREFOR CHEMISTRY COMPOUNDS THEREOF GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS INORGANIC CHEMISTRY METALLURGY NON-METALLIC ELEMENTS ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	This invention provides a stereospecific process for the synthesis of (S)-(+)-N,N-dimethyl-3-(1- naphthalenyloxy)-3-(2-thienyl)propanamine, a key intermediate in the synthesis of duloxetine.